New publication


Our manuscript “The Influence of Transcription Factor Competition on the Relationship between Occupancy and Affinity” has now been published in PLoS ONE. We summarised the main findings in a few other blog posts, and it’s not a long one, so why don’t you have a quick read of the abstract at PLoS. Just a quick note that I personally find the most striking figure of the manuscript is the comparison “SDO and ADO landscape for various cognate and non-cognate abundances”. That’s a really intuitive display for a genome gazer like myself. You’ve probably seen similar also in Mike Eisen’s paper “Quantitative models of the mechanisms that control genome-wide patterns of transcription factor binding during early Drosophila development.“. However, in contrast to their paper, we include the R code to generate the profiles in the Supplementary Material.

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