New publication

binding

Our manuscript “The Influence of Transcription Factor Competition on the Relationship between Occupancy and Affinity” has now been published in PLoS ONE. We summarised the main findings in a few other blog posts, and it’s not a long one, so why don’t you have a quick read of the abstract at PLoS. Just a quick note that I personally find the most striking figure of the manuscript is the comparison “SDO and ADO landscape for various cognate and non-cognate abundances”. That’s a really intuitive display for a genome gazer like myself. You’ve probably seen similar also in Mike Eisen’s paper “Quantitative models of the mechanisms that control genome-wide patterns of transcription factor binding during early Drosophila development.“. However, in contrast to their paper, we include the R code to generate the profiles in the Supplementary Material.

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