Tracheal system goes lung development

copd_teaserA couple of months ago I was asked to join the European Cooperation in Science and Technology (COST) action on “Developmental Origins of Chronic Lung Disease“. While we are in the first instance a transcriptional regulation lab and in the second instance a developmental biology group, we are surely not a disease-oriented group. However, the data integration strategies needed in the understanding of transcriptional regulation and genome-wide studies in general allow us to compare large datasets between fly and human. So I’ve decided to showcase the intersection of Christos Samakovlis‘ very detailed study of RNAi phenotypes in the developing tracheal system of Drosophila with genome-wide association studies in lung disease. I’m going to present these initial results at the COST Conference at Starnberger See this week. We’re quite excited about the results, so let’s see what the lung development and disease communities have to say.

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